Myelomatous plasma cells display an aberrant gene expression pattern similar to that observed in normal memory B cells

Memory B cells (MBCs) remain in a quiescent state for years, expressing pro-survival and anti-apoptotic factors while repressing cell proliferation and activation genes. During their differentiation into plasma cells (PCs), their expression pattern is reversed, with a higher expression of genes rela...

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Detalhes bibliográficos
Publicado no:Am J Cancer Res
Main Authors: Báez, Alicia, Piruat, José I, Caballero-Velázquez, Teresa, Sánchez-Abarca, Luís I, Álvarez-Laderas, Isabel, Barbado, M Victoria, García-Guerrero, Estefanía, Millán-Uclés, África, Martín-Sánchez, Jesús, Medrano, Mayte, Pérez-Simón, José Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4300706/
https://ncbi.nlm.nih.gov/pubmed/25628947
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