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Targeting cancer-specific mutations by T cell receptor gene therapy
The ease of sequencing the cancer genome, identifying all somatic mutations and grafting mutation-specific T cell receptor (TCR) genes into T cells for adoptive transfer allow, for the first time, a truly tumor-specific and effective therapy. Mutation-specific TCR gene therapy might achieve optimal...
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| 發表在: | Curr Opin Immunol |
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| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4557613/ https://ncbi.nlm.nih.gov/pubmed/25728991 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2015.02.005 |
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