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Targeting human melanoma neoantigens by T cell receptor gene therapy
In successful cancer immunotherapy, T cell responses appear to be directed toward neoantigens created by somatic mutations; however, direct evidence that neoantigen-specific T cells cause regression of established cancer is lacking. Here, we generated T cells expressing a mutation-specific transgeni...
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| Publicado no: | J Clin Invest |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4767365/ https://ncbi.nlm.nih.gov/pubmed/26808500 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI83465 |
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