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“Designer cytokines” targeting the tumor vasculature—think global and act local

Tumor necrosis factor (TNF) was discovered in 1975 as a lipopolysaccharide‐induced serum factor that causes necrosis of tumors (Carswell et al, 1975). It was later found that TNF and cachectin, a factor causing wasting disease, were one and the same molecule (Beutler et al, 1985). Studies on the inf...

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Vydáno v:EMBO Mol Med
Hlavní autoři: Kammertoens, Thomas, Kemna, Josephine, Leisegang, Matthias
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7005528/
https://ncbi.nlm.nih.gov/pubmed/31916677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201911801
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