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“Designer cytokines” targeting the tumor vasculature—think global and act local
Tumor necrosis factor (TNF) was discovered in 1975 as a lipopolysaccharide‐induced serum factor that causes necrosis of tumors (Carswell et al, 1975). It was later found that TNF and cachectin, a factor causing wasting disease, were one and the same molecule (Beutler et al, 1985). Studies on the inf...
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| Publicado en: | EMBO Mol Med |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
John Wiley and Sons Inc.
2020
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7005528/ https://ncbi.nlm.nih.gov/pubmed/31916677 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201911801 |
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