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Protective Capacity of Virus-Specific T Cell Receptor-Transduced CD8 T Cells In Vivo

The transfer of T cell receptor (TCR) genes by viral vectors represents a promising technique to generate antigen-specific T cells for adoptive immunotherapy. TCR-transduced T cells specific for infectious pathogens have been described, but their protective function in vivo has not yet been examined...

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Detalhes bibliográficos
Main Authors: Mueller, Katja, von Mässenhausen, Anne, Aichele, Ulrike, Stärck, Lilian, Leisegang, Matthias, Uckert, Wolfgang, Pircher, Hanspeter
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457306/
https://ncbi.nlm.nih.gov/pubmed/22787223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01472-12
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