RNAseq expression analysis of resistant and susceptible mice after influenza A virus infection identifies novel genes associated with virus replication and important for host resistance to infection

BACKGROUND: The host response to influenza A infections is strongly influenced by host genetic factors. Animal models of genetically diverse mouse strains are well suited to identify host genes involved in severe pathology, viral replication and immune responses. Here, we have utilized a dual RNAseq...

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Vydáno v:BMC Genomics
Hlavní autoři: Wilk, Esther, Pandey, Ashutosh K., Leist, Sarah Rebecca, Hatesuer, Bastian, Preusse, Matthias, Pommerenke, Claudia, Wang, Junxi, Schughart, Klaus
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4557482/
https://ncbi.nlm.nih.gov/pubmed/26329040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-015-1867-8
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