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RNAseq expression analysis of resistant and susceptible mice after influenza A virus infection identifies novel genes associated with virus replication and important for host resistance to infection

BACKGROUND: The host response to influenza A infections is strongly influenced by host genetic factors. Animal models of genetically diverse mouse strains are well suited to identify host genes involved in severe pathology, viral replication and immune responses. Here, we have utilized a dual RNAseq...

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Bibliografiske detaljer
Udgivet i:BMC Genomics
Main Authors: Wilk, Esther, Pandey, Ashutosh K., Leist, Sarah Rebecca, Hatesuer, Bastian, Preusse, Matthias, Pommerenke, Claudia, Wang, Junxi, Schughart, Klaus
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4557482/
https://ncbi.nlm.nih.gov/pubmed/26329040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-015-1867-8
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