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RNAseq expression analysis of resistant and susceptible mice after influenza A virus infection identifies novel genes associated with virus replication and important for host resistance to infection

BACKGROUND: The host response to influenza A infections is strongly influenced by host genetic factors. Animal models of genetically diverse mouse strains are well suited to identify host genes involved in severe pathology, viral replication and immune responses. Here, we have utilized a dual RNAseq...

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Publicat a:BMC Genomics
Autors principals: Wilk, Esther, Pandey, Ashutosh K., Leist, Sarah Rebecca, Hatesuer, Bastian, Preusse, Matthias, Pommerenke, Claudia, Wang, Junxi, Schughart, Klaus
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4557482/
https://ncbi.nlm.nih.gov/pubmed/26329040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-015-1867-8
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