RNAseq expression analysis of resistant and susceptible mice after influenza A virus infection identifies novel genes associated with virus replication and important for host resistance to infection

BACKGROUND: The host response to influenza A infections is strongly influenced by host genetic factors. Animal models of genetically diverse mouse strains are well suited to identify host genes involved in severe pathology, viral replication and immune responses. Here, we have utilized a dual RNAseq...

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Bibliografiska uppgifter
I publikationen:BMC Genomics
Huvudupphovsmän: Wilk, Esther, Pandey, Ashutosh K., Leist, Sarah Rebecca, Hatesuer, Bastian, Preusse, Matthias, Pommerenke, Claudia, Wang, Junxi, Schughart, Klaus
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2015
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4557482/
https://ncbi.nlm.nih.gov/pubmed/26329040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-015-1867-8
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