Identification of mammalian-adapting mutations in the polymerase complex of an avian H5N1 influenza virus

Avian influenza viruses of the H5N1 subtype pose a serious global health threat due to the high mortality (>60%) associated with the disease caused by these viruses and the lack of protective antibodies to these viruses in the general population. The factors that enable avian H5N1 influenza virus...

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Bibliografiska uppgifter
I publikationen:Nat Commun
Huvudupphovsmän: Taft, Andrew S., Ozawa, Makoto, Fitch, Adam, Depasse, Jay V., Halfmann, Peter J., Hill-Batorski, Lindsay, Hatta, Masato, Friedrich, Thomas C., Lopes, Tiago J. S., Maher, Eileen A., Ghedin, Elodie, Macken, Catherine A., Neumann, Gabriele, Kawaoka, Yoshihiro
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2015
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4557292/
https://ncbi.nlm.nih.gov/pubmed/26082035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8491
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