Glucagon sensitivity and clearance in type 1 diabetes: insights from in vivo and in silico experiments

Glucagon use in artificial pancreas for type 1 diabetes (T1D) is being explored for prevention and rescue from hypoglycemia. However, the relationship between glucagon stimulation of endogenous glucose production (EGP) viz., hepatic glucagon sensitivity, and prevailing glucose concentrations has not...

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Pubblicato in:Am J Physiol Endocrinol Metab
Autori principali: Hinshaw, Ling, Mallad, Ashwini, Dalla Man, Chiara, Basu, Rita, Cobelli, Claudio, Carter, Rickey E., Kudva, Yogish C., Basu, Ananda
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2015
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4556882/
https://ncbi.nlm.nih.gov/pubmed/26152766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00236.2015
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