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Glucagon sensitivity and clearance in type 1 diabetes: insights from in vivo and in silico experiments

Glucagon use in artificial pancreas for type 1 diabetes (T1D) is being explored for prevention and rescue from hypoglycemia. However, the relationship between glucagon stimulation of endogenous glucose production (EGP) viz., hepatic glucagon sensitivity, and prevailing glucose concentrations has not...

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Bibliografische gegevens
Gepubliceerd in:Am J Physiol Endocrinol Metab
Hoofdauteurs: Hinshaw, Ling, Mallad, Ashwini, Dalla Man, Chiara, Basu, Rita, Cobelli, Claudio, Carter, Rickey E., Kudva, Yogish C., Basu, Ananda
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Physiological Society 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4556882/
https://ncbi.nlm.nih.gov/pubmed/26152766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00236.2015
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