Glucagon sensitivity and clearance in type 1 diabetes: insights from in vivo and in silico experiments

Glucagon use in artificial pancreas for type 1 diabetes (T1D) is being explored for prevention and rescue from hypoglycemia. However, the relationship between glucagon stimulation of endogenous glucose production (EGP) viz., hepatic glucagon sensitivity, and prevailing glucose concentrations has not...

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Bibliographic Details
Published in:Am J Physiol Endocrinol Metab
Main Authors: Hinshaw, Ling, Mallad, Ashwini, Dalla Man, Chiara, Basu, Rita, Cobelli, Claudio, Carter, Rickey E., Kudva, Yogish C., Basu, Ananda
Format: Artigo
Language:Inglês
Published: American Physiological Society 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4556882/
https://ncbi.nlm.nih.gov/pubmed/26152766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00236.2015
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