Glucagon sensitivity and clearance in type 1 diabetes: insights from in vivo and in silico experiments

Glucagon use in artificial pancreas for type 1 diabetes (T1D) is being explored for prevention and rescue from hypoglycemia. However, the relationship between glucagon stimulation of endogenous glucose production (EGP) viz., hepatic glucagon sensitivity, and prevailing glucose concentrations has not...

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Veröffentlicht in:Am J Physiol Endocrinol Metab
Hauptverfasser: Hinshaw, Ling, Mallad, Ashwini, Dalla Man, Chiara, Basu, Rita, Cobelli, Claudio, Carter, Rickey E., Kudva, Yogish C., Basu, Ananda
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2015
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4556882/
https://ncbi.nlm.nih.gov/pubmed/26152766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00236.2015
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