Glucagon sensitivity and clearance in type 1 diabetes: insights from in vivo and in silico experiments

Glucagon use in artificial pancreas for type 1 diabetes (T1D) is being explored for prevention and rescue from hypoglycemia. However, the relationship between glucagon stimulation of endogenous glucose production (EGP) viz., hepatic glucagon sensitivity, and prevailing glucose concentrations has not...

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Detalhes bibliográficos
Publicado no:Am J Physiol Endocrinol Metab
Main Authors: Hinshaw, Ling, Mallad, Ashwini, Dalla Man, Chiara, Basu, Rita, Cobelli, Claudio, Carter, Rickey E., Kudva, Yogish C., Basu, Ananda
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4556882/
https://ncbi.nlm.nih.gov/pubmed/26152766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00236.2015
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