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Analysis of Dengue Virus Genetic Diversity during Human and Mosquito Infection Reveals Genetic Constraints

Dengue viruses (DENV) cause debilitating and potentially life-threatening acute disease throughout the tropical world. While drug development efforts are underway, there are concerns that resistant strains will emerge rapidly. Indeed, antiviral drugs that target even conserved regions in other RNA v...

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Détails bibliographiques
Publié dans:PLoS Negl Trop Dis
Auteurs principaux: Sessions, October M., Wilm, Andreas, Kamaraj, Uma Sangumathi, Choy, Milly M., Chow, Angelia, Chong, Yuwen, Ong, Xin Mei, Nagarajan, Niranjan, Cook, Alex R., Ooi, Eng Eong
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4556638/
https://ncbi.nlm.nih.gov/pubmed/26327586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0004044
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