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Analysis of Dengue Virus Genetic Diversity during Human and Mosquito Infection Reveals Genetic Constraints

Dengue viruses (DENV) cause debilitating and potentially life-threatening acute disease throughout the tropical world. While drug development efforts are underway, there are concerns that resistant strains will emerge rapidly. Indeed, antiviral drugs that target even conserved regions in other RNA v...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Sessions, October M., Wilm, Andreas, Kamaraj, Uma Sangumathi, Choy, Milly M., Chow, Angelia, Chong, Yuwen, Ong, Xin Mei, Nagarajan, Niranjan, Cook, Alex R., Ooi, Eng Eong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4556638/
https://ncbi.nlm.nih.gov/pubmed/26327586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0004044
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