Analysis of Dengue Virus Genetic Diversity during Human and Mosquito Infection Reveals Genetic Constraints

Dengue viruses (DENV) cause debilitating and potentially life-threatening acute disease throughout the tropical world. While drug development efforts are underway, there are concerns that resistant strains will emerge rapidly. Indeed, antiviral drugs that target even conserved regions in other RNA v...

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Vydáno v:PLoS Negl Trop Dis
Hlavní autoři: Sessions, October M., Wilm, Andreas, Kamaraj, Uma Sangumathi, Choy, Milly M., Chow, Angelia, Chong, Yuwen, Ong, Xin Mei, Nagarajan, Niranjan, Cook, Alex R., Ooi, Eng Eong
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4556638/
https://ncbi.nlm.nih.gov/pubmed/26327586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0004044
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