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MIWI2 and MILI Have Differential Effects on piRNA Biogenesis and DNA Methylation
In developing male germ cells, prospermatogonia, two Piwi proteins, MILI and MIWI2, use Piwi-interacting RNA (piRNA) guides to repress transposable element (TE) expression and ensure genome stability and proper gametogenesis. In addition to their roles in post-transcriptional TE repression, both pro...
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| Udgivet i: | Cell Rep |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4554733/ https://ncbi.nlm.nih.gov/pubmed/26279574 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.07.036 |
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