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Single methylation of 23S rRNA triggers late steps of 50S ribosomal subunit assembly
Ribosome biogenesis requires multiple assembly factors. In Escherichia coli, deletion of RlmE, the methyltransferase responsible for the 2′-O-methyluridine modification at position 2552 (Um2552) in helix 92 of the 23S rRNA, results in slow growth and accumulation of the 45S particle. We demonstrate...
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| Izdano u: | Proc Natl Acad Sci U S A |
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| Glavni autori: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2015
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4553768/ https://ncbi.nlm.nih.gov/pubmed/26261349 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1506749112 |
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