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Single methylation of 23S rRNA triggers late steps of 50S ribosomal subunit assembly

Ribosome biogenesis requires multiple assembly factors. In Escherichia coli, deletion of RlmE, the methyltransferase responsible for the 2′-O-methyluridine modification at position 2552 (Um2552) in helix 92 of the 23S rRNA, results in slow growth and accumulation of the 45S particle. We demonstrate...

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Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Arai, Taiga, Ishiguro, Kensuke, Kimura, Satoshi, Sakaguchi, Yuriko, Suzuki, Takeo, Suzuki, Tsutomu
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4553768/
https://ncbi.nlm.nih.gov/pubmed/26261349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1506749112
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