The Interleukin-13 Receptor-α1 Chain Is Essential for Induction of the Alternative Macrophage Activation Pathway by IL-13 but Not IL-4

Macrophages coexpress both the interleukin (IL)-2Rγ chain (γ(c)) and IL-13Rα1. These receptor chains can heterodimerize with IL-4Rα to form type I or type II IL-4 receptor complexes, respectively. We used macrophages derived from Il2rg and Il13ra1 knockout (KO) mice to evaluate the requirements for...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:J Innate Immun
Huvudupphovsmän: Sheikh, Faruk, Dickensheets, Harold, Pedras-Vasconcelos, Joao, Ramalingam, Thirumalai, Helming, Laura, Gordon, Siamon, Donnelly, Raymond P.
Materialtyp: Artigo
Språk:Inglês
Publicerad: S. Karger AG 2015
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4553078/
https://ncbi.nlm.nih.gov/pubmed/25766112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000376579
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk