Unique functions of the type II interleukin 4 receptor identified in mice lacking the interleukin 13 receptor α1 chain

The interleukin 4 receptor (IL-4R) is a central mediator of T helper type 2 (T(H)2)–mediated disease and associates with either the common γ-chain to form the type I IL-4R or with the IL-13R α1 chain (IL-13Rα1) to form the type II IL-4R. Here we used Il13ra1(−/−) mice to characterize the distinct fu...

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Main Authors: Ramalingam, Thirumalai R, Pesce, John T, Sheikh, Faruk, Cheever, Allen W, Mentink-Kane, Margaret M, Wilson, Mark S, Stevens, Sean, Valenzuela, David M, Murphy, Andrew J, Yancopoulos, George D, Urban, Joseph F, Donnelly, Raymond P, Wynn, Thomas A
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2692551/
https://ncbi.nlm.nih.gov/pubmed/18066066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni1544
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