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Predicting the spatial organization of chromosomes using epigenetic data

Chromosome folding can reinforce the demarcation between euchromatin and heterochromatin. Two new studies show how epigenetic data, including DNA methylation, can accurately predict chromosome folding in three dimensions. Such computational approaches reinforce the idea of a linkage between epigenet...

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Mourad, Raphaël, Cuvier, Olivier
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4552987/
https://ncbi.nlm.nih.gov/pubmed/26319942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-015-0752-8
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