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Computational Identification of Genomic Features That Influence 3D Chromatin Domain Formation

Recent advances in long-range Hi-C contact mapping have revealed the importance of the 3D structure of chromosomes in gene expression. A current challenge is to identify the key molecular drivers of this 3D structure. Several genomic features, such as architectural proteins and functional elements,...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Mourad, Raphaël, Cuvier, Olivier
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4874696/
https://ncbi.nlm.nih.gov/pubmed/27203237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004908
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