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Uncovering direct and indirect molecular determinants of chromatin loops using a computational integrative approach
Chromosomal organization in 3D plays a central role in regulating cell-type specific transcriptional and DNA replication timing programs. Yet it remains unclear to what extent the resulting long-range contacts depend on specific molecular drivers. Here we propose a model that comprehensively assesse...
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| Publicado no: | PLoS Comput Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5462476/ https://ncbi.nlm.nih.gov/pubmed/28542178 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005538 |
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