Reduced Occurrence of Tumor Flare with Flavopiridol Followed by Combined Flavopiridol and Lenalidomidein Patients with Relapsed Chronic Lymphocytic Leukemia (CLL)

Flavopiridol and lenalidomide have activity in refractory CLL without immunosuppression or opportunistic infections seen with other therapies. We hypothesized that flavopiridol treatment could adequately de-bulk disease prior to lenalidomide therapy, decreasing the incidence of tumor flare with high...

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Опубликовано в: :Am J Hematol
Главные авторы: Maddocks, Kami, Wei, Lai, Rozewski, Darlene, Jiang, Yao, Zhao, Yuan, Adusumilli, Mikhil, Pierceall, William E., Doykin, Camille, Cardone, Michael H., Jones, Jeffrey A., Flynn, Joseph, Andritsos, Leslie A., Grever, Michael R., Byrd, John C., Johnson, Amy J., Phelps, Mitch A., Blum, Kristie A
Формат: Artigo
Язык:Inglês
Опубликовано: 2015
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4552311/
https://ncbi.nlm.nih.gov/pubmed/25639448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajh.23946
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