A novel liposomal formulation of flavopiridol

Flavopiridol has shown promising activities in hematologic and solid tumor models, as well as in clinical trials in chronic lymphocytic leukemia patients. Flavopiridol has relatively low solubility and high plasma protein-binding. To address these issues and to provide an alternative strategy to ach...

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Bibliografiske detaljer
Main Authors: Yang, Xiaojuan, Zhao, Xiaobin, Phelps, Mitch A., Piao, Longzhu, Rozewski, Darlene M., Liu, Qing, Lee, L. James, Marcucci, Guido, Grever, Michael R., Byrd, John C., Dalton, James T., Lee, Robert J.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3035394/
https://ncbi.nlm.nih.gov/pubmed/18778761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2008.08.008
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