A novel liposomal formulation of flavopiridol

Flavopiridol has shown promising activities in hematologic and solid tumor models, as well as in clinical trials in chronic lymphocytic leukemia patients. Flavopiridol has relatively low solubility and high plasma protein-binding. To address these issues and to provide an alternative strategy to ach...

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Detalhes bibliográficos
Main Authors: Yang, Xiaojuan, Zhao, Xiaobin, Phelps, Mitch A., Piao, Longzhu, Rozewski, Darlene M., Liu, Qing, Lee, L. James, Marcucci, Guido, Grever, Michael R., Byrd, John C., Dalton, James T., Lee, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3035394/
https://ncbi.nlm.nih.gov/pubmed/18778761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2008.08.008
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