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Developmental regulation of planar cell polarity and hair bundle morphogenesis in auditory hair cells: lessons from human and mouse genetics

Hearing loss is the most common and costly sensory defect in humans, and genetic causes underlie a significant proportion of affected individuals. In mammals, sound is detected by hair cells housed in the cochlea of the inner ear, whose function depends on a highly specialized mechanotransduction or...

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Bibliographische Detailangaben
Veröffentlicht in:Wiley Interdiscip Rev Dev Biol
Hauptverfasser: Lu, Xiaowei, Sipe, Conor W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4552040/
https://ncbi.nlm.nih.gov/pubmed/26265594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/wdev.202
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