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The Small GTPase Rac1 Regulates Auditory Hair Cell Morphogenesis

Morphogenesis of sensory hair cells, in particular their mechanotransduction organelle, the stereociliary bundle, requires highly organized remodeling of the actin cytoskeleton. The roles of Rho family small GTPases during this process remain unknown. Here we show that deletion of Rac1 in the otic e...

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Hlavní autoři: Grimsley-Myers, Cynthia M., Sipe, Conor W., Géléoc, Gwenaëlle S. G., Lu, Xiaowei
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847287/
https://ncbi.nlm.nih.gov/pubmed/20016102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3998-09.2009
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