Lis1 mediates planar polarity of auditory hair cells through regulation of microtubule organization

The V-shaped hair bundles atop auditory hair cells and their uniform orientation are manifestations of epithelial planar cell polarity (PCP) required for proper perception of sound. PCP is regulated at the tissue level by a conserved core Wnt/PCP pathway. However, the hair cell-intrinsic polarity ma...

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Detaylı Bibliyografya
Asıl Yazarlar: Sipe, Conor W., Liu, Lixia, Lee, Jianyi, Grimsley-Myers, Cynthia, Lu, Xiaowei
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Company of Biologists 2013
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3621493/
https://ncbi.nlm.nih.gov/pubmed/23533177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.089763
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