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Structural and functional studies of the Mycobacterium tuberculosis VapBC30 toxin-antitoxin system: implications for the design of novel antimicrobial peptides

Toxin-antitoxin (TA) systems play important roles in bacterial physiology, such as multidrug tolerance, biofilm formation, and arrest of cellular growth under stress conditions. To develop novel antimicrobial agents against tuberculosis, we focused on VapBC systems, which encompass more than half of...

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Foilsithe in:Nucleic Acids Res
Main Authors: Lee, In-Gyun, Lee, Sang Jae, Chae, Susanna, Lee, Ki-Young, Kim, Ji-Hun, Lee, Bong-Jin
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4551927/
https://ncbi.nlm.nih.gov/pubmed/26150422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv689
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