Functional details of the Mycobacterium tuberculosis VapBC26 toxin-antitoxin system based on a structural study: insights into unique binding and antibiotic peptides

Toxin-antitoxin (TA) systems are essential for bacterial persistence under stressful conditions. In particular, Mycobacterium tuberculosis express VapBC TA genes that encode the stable VapC toxin and the labile VapB antitoxin. Under normal conditions, these proteins interact to form a non-toxic TA c...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Kang, Sung-Min, Kim, Do-Hee, Lee, Ki-Young, Park, Sung Jean, Yoon, Hye-Jin, Lee, Sang Jae, Im, Hookang, Lee, Bong-Jin
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Structural Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5737657/
https://ncbi.nlm.nih.gov/pubmed/28575388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx489
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