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Functional details of the Mycobacterium tuberculosis VapBC26 toxin-antitoxin system based on a structural study: insights into unique binding and antibiotic peptides

Toxin-antitoxin (TA) systems are essential for bacterial persistence under stressful conditions. In particular, Mycobacterium tuberculosis express VapBC TA genes that encode the stable VapC toxin and the labile VapB antitoxin. Under normal conditions, these proteins interact to form a non-toxic TA c...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Kang, Sung-Min, Kim, Do-Hee, Lee, Ki-Young, Park, Sung Jean, Yoon, Hye-Jin, Lee, Sang Jae, Im, Hookang, Lee, Bong-Jin
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2017
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5737657/
https://ncbi.nlm.nih.gov/pubmed/28575388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx489
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