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Generation of supercoils in nicked and gapped DNA drives DNA unknotting and postreplicative decatenation

Due to the helical structure of DNA the process of DNA replication is topologically complex. Freshly replicated DNA molecules are catenated with each other and are frequently knotted. For proper functioning of DNA it is necessary to remove all of these entanglements. This is done by DNA topoisomeras...

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書目詳細資料
發表在:Nucleic Acids Res
Main Authors: Racko, Dusan, Benedetti, Fabrizio, Dorier, Julien, Burnier, Yannis, Stasiak, Andrzej
格式: Artigo
語言:Inglês
出版: Oxford University Press 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4551925/
https://ncbi.nlm.nih.gov/pubmed/26150424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv683
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