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Generation of supercoils in nicked and gapped DNA drives DNA unknotting and postreplicative decatenation
Due to the helical structure of DNA the process of DNA replication is topologically complex. Freshly replicated DNA molecules are catenated with each other and are frequently knotted. For proper functioning of DNA it is necessary to remove all of these entanglements. This is done by DNA topoisomeras...
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| Udgivet i: | Nucleic Acids Res |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4551925/ https://ncbi.nlm.nih.gov/pubmed/26150424 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv683 |
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