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Prior knowledge driven Granger causality analysis on gene regulatory network discovery

BACKGROUND: Our study focuses on discovering gene regulatory networks from time series gene expression data using the Granger causality (GC) model. However, the number of available time points (T) usually is much smaller than the number of target genes (n) in biological datasets. The widely applied...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Yao, Shun, Yoo, Shinjae, Yu, Dantong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4551367/
https://ncbi.nlm.nih.gov/pubmed/26316173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-015-0710-1
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