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Reconstruction of gene networks using prior knowledge

BACKGROUND: Reconstructing gene regulatory networks (GRNs) from expression data is a challenging task that has become essential to the understanding of complex regulatory mechanisms in cells. The major issues are the usually very high ratio of number of genes to sample size, and the noise in the ava...

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Detalhes bibliográficos
Publicado no:BMC Syst Biol
Main Authors: Ghanbari, Mahsa, Lasserre, Julia, Vingron, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4654848/
https://ncbi.nlm.nih.gov/pubmed/26589494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-015-0233-4
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