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Prior knowledge driven Granger causality analysis on gene regulatory network discovery

BACKGROUND: Our study focuses on discovering gene regulatory networks from time series gene expression data using the Granger causality (GC) model. However, the number of available time points (T) usually is much smaller than the number of target genes (n) in biological datasets. The widely applied...

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Dades bibliogràfiques
Publicat a:BMC Bioinformatics
Autors principals: Yao, Shun, Yoo, Shinjae, Yu, Dantong
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4551367/
https://ncbi.nlm.nih.gov/pubmed/26316173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-015-0710-1
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