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Prior knowledge driven Granger causality analysis on gene regulatory network discovery

BACKGROUND: Our study focuses on discovering gene regulatory networks from time series gene expression data using the Granger causality (GC) model. However, the number of available time points (T) usually is much smaller than the number of target genes (n) in biological datasets. The widely applied...

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Pubblicato in:BMC Bioinformatics
Autori principali: Yao, Shun, Yoo, Shinjae, Yu, Dantong
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4551367/
https://ncbi.nlm.nih.gov/pubmed/26316173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-015-0710-1
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