Serial monitoring of circulating tumor DNA in patients with primary breast cancer for detection of occult metastatic disease

Metastatic breast cancer is usually diagnosed after becoming symptomatic, at which point it is rarely curable. Cell-free circulating tumor DNA (ctDNA) contains tumor-specific chromosomal rearrangements that may be interrogated in blood plasma. We evaluated serial monitoring of ctDNA for earlier dete...

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Detalhes bibliográficos
Publicado no:EMBO Mol Med
Main Authors: Olsson, Eleonor, Winter, Christof, George, Anthony, Chen, Yilun, Howlin, Jillian, Tang, Man-Hung Eric, Dahlgren, Malin, Schulz, Ralph, Grabau, Dorthe, van Westen, Danielle, Fernö, Mårten, Ingvar, Christian, Rose, Carsten, Bendahl, Pär-Ola, Rydén, Lisa, Borg, Åke, Gruvberger-Saal, Sofia K, Jernström, Helena, Saal, Lao H
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4551342/
https://ncbi.nlm.nih.gov/pubmed/25987569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201404913
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