Serial monitoring of circulating tumor DNA in patients with primary breast cancer for detection of occult metastatic disease

Metastatic breast cancer is usually diagnosed after becoming symptomatic, at which point it is rarely curable. Cell-free circulating tumor DNA (ctDNA) contains tumor-specific chromosomal rearrangements that may be interrogated in blood plasma. We evaluated serial monitoring of ctDNA for earlier dete...

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Veröffentlicht in:EMBO Mol Med
Hauptverfasser: Olsson, Eleonor, Winter, Christof, George, Anthony, Chen, Yilun, Howlin, Jillian, Tang, Man-Hung Eric, Dahlgren, Malin, Schulz, Ralph, Grabau, Dorthe, van Westen, Danielle, Fernö, Mårten, Ingvar, Christian, Rose, Carsten, Bendahl, Pär-Ola, Rydén, Lisa, Borg, Åke, Gruvberger-Saal, Sofia K, Jernström, Helena, Saal, Lao H
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley & Sons, Ltd 2015
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Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4551342/
https://ncbi.nlm.nih.gov/pubmed/25987569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201404913
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