Remarkable similarities of chromosomal rearrangements between primary human breast cancers and matched distant metastases as revealed by whole-genome sequencing

To better understand and characterize chromosomal structural variation during breast cancer progression, we enumerated chromosomal rearrangements for 11 patients by performing low-coverage whole-genome sequencing of 11 primary breast tumors and their 13 matched distant metastases. The tumor genomes...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Tang, Man-Hung Eric, Dahlgren, Malin, Brueffer, Christian, Tjitrowirjo, Tamara, Winter, Christof, Chen, Yilun, Olsson, Eleonor, Wang, Kun, Törngren, Therese, Sjöström, Martin, Grabau, Dorthe, Bendahl, Pär-Ola, Rydén, Lisa, Niméus, Emma, Saal, Lao H., Borg, Åke, Gruvberger-Saal, Sofia K.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741922/
https://ncbi.nlm.nih.gov/pubmed/26439695
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