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Global H3K27 trimethylation and EZH2 abundance in breast tumor subtypes
Polycomb repressive complex 2 (PRC2) and its core member enhancer of zeste homolog 2 (EZH2) mediate the epigenetic gene silencing mark: trimethylation of lysine 27 on histone 3 (H3K27me3). H3K27me3 is characteristic of the chromatin at genes involved in developmental regulation in undifferentiated c...
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| Publicado no: | Mol Oncol |
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| Main Authors: | , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5528390/ https://ncbi.nlm.nih.gov/pubmed/22766277 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2012.06.002 |
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