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Fulfilling the Promise of "Biased" G Protein–Coupled Receptor Agonism
The fact that over 30% of current pharmaceuticals target heptahelical G protein–coupled receptors (GPCRs) attests to their tractability as drug targets. Although GPCR drug development has traditionally focused on conventional agonists and antagonists, the growing appreciation that GPCRs mediate phys...
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| Publicado en: | Mol Pharmacol |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
The American Society for Pharmacology and Experimental Therapeutics
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4551052/ https://ncbi.nlm.nih.gov/pubmed/26134495 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.115.099630 |
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