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Analysis of YFP(J16)-R6/2 reporter mice and postmortem brains reveals early pathology and increased vulnerability of callosal axons in Huntington's disease

Cumulative evidence indicates that the onset and severity of Huntington's disease (HD) symptoms correlate with connectivity deficits involving specific neuronal populations within cortical and basal ganglia circuits. Brain imaging studies and pathological reports further associated these defici...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Hum Mol Genet
मुख्य लेखकों: Gatto, Rodolfo G., Chu, Yaping, Ye, Allen Q., Price, Steven D., Tavassoli, Ehsan, Buenaventura, Andrea, Brady, Scott T., Magin, Richard L., Kordower, Jeffrey H., Morfini, Gerardo A.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Oxford University Press 2015
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4550824/
https://ncbi.nlm.nih.gov/pubmed/26123489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv248
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