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Analysis of YFP(J16)-R6/2 reporter mice and postmortem brains reveals early pathology and increased vulnerability of callosal axons in Huntington's disease

Cumulative evidence indicates that the onset and severity of Huntington's disease (HD) symptoms correlate with connectivity deficits involving specific neuronal populations within cortical and basal ganglia circuits. Brain imaging studies and pathological reports further associated these defici...

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Detaylı Bibliyografya
Yayımlandı:Hum Mol Genet
Asıl Yazarlar: Gatto, Rodolfo G., Chu, Yaping, Ye, Allen Q., Price, Steven D., Tavassoli, Ehsan, Buenaventura, Andrea, Brady, Scott T., Magin, Richard L., Kordower, Jeffrey H., Morfini, Gerardo A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4550824/
https://ncbi.nlm.nih.gov/pubmed/26123489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv248
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