Novel analogues of chlormethiazole are neuroprotective in four cellular models of neurodegeneration by a mechanism with variable dependence on GABA(A) receptor potentiation

Por VandeVrede, Lawren, Tavassoli, Ehsan, Luo, Jia, Qin, Zhihui, Yue, Lan, Pepperberg, David R, Thatcher, Gregory R
Publicado em 2014

Design and Synthesis of Neuroprotective Methylthiazoles and Modification as NO-Chimeras for Neurodegenerative Therapy

Por Qin, Zhihui, Luo, Jia, VandeVrede, Lawren, Tavassoli, Ehsan, Fa’, Mauro, Teich, Andrew, Arancio, Ottavio, Thatcher, Gregory R. J.
Publicado em 2012

Analysis of YFP(J16)-R6/2 reporter mice and postmortem brains reveals early pathology and increased vulnerability of callosal axons in Huntington's disease

Por Gatto, Rodolfo G., Chu, Yaping, Ye, Allen Q., Price, Steven D., Tavassoli, Ehsan, Buenaventura, Andrea, Brady, Scott T., Magin, Richard L., Kordower, Jeffrey H., Morfini, Gerardo A.
Publicado no Hum Mol Genet (2015)

NO-SSRIs: Nitric Oxide Chimera Drugs Incorporating a Selective Serotonin Reuptake Inhibitor

Por Abdul-Hay, Samer, Schiefer, Isaac T., Chandrasena, R. Esala P., Li, Min, Abdelhamid, Ramy, Wang, Yue-Ting, Tavassoli, Ehsan, Michalsen, Bradley, Asghodom, Rezene T., Luo, Jia, Thatcher, Gregory R. J.
Publicado em 2011

Design, Synthesis, and Optimization of Novel Epoxide Incorporating Peptidomimetics as Selective Calpain Inhibitors

Por Schiefer, Isaac T., Tapadar, Subhasish, Litosh, Vladislav, Siklos, Marton, Scism, Rob, Wijewickrama, Gihani T., Chandrasena, Esala P., Sinha, Vaishali, Tavassoli, Ehsan, Brunsteiner, Michael, Fa′, Mauro, Arancio, Ottavio, Petukhov, Pavel, Thatcher, Gregory R. J.
Publicado em 2013

Re-engineering a neuroprotective, clinical drug as a procognitive agent with high in vivo potency and with GABA(A) potentiating activity for use in dementia

Por Luo, Jia, Lee, Sue H., VandeVrede, Lawren, Qin, Zhihui, Piyankarage, Sujeewa, Tavassoli, Ehsan, Asghodom, Rezene T., Aissa, Manel Ben, Fà, Mauro, Arancio, Ottavio, Yue, Lan, Pepperberg, David R., Thatcher, Gregory R. J.
Publicado no BMC Neurosci (2015)

Inhibition of Fast Axonal Transport by Pathogenic SOD1 Involves Activation of p38 MAP Kinase

Por Morfini, Gerardo A., Bosco, Daryl A., Brown, Hannah, Gatto, Rodolfo, Kaminska, Agnieszka, Song, Yuyu, Molla, Linda, Baker, Lisa, Marangoni, M. Natalia, Berth, Sarah, Tavassoli, Ehsan, Bagnato, Carolina, Tiwari, Ashutosh, Hayward, Lawrence J., Pigino, Gustavo F., Watterson, D. Martin, Huang, Chun-Fang, Banker, Gary, Brown, Robert H., Brady, Scott T.
Publicado em 2013