Detection of axonal degeneration in a mouse model of Huntington’s disease: comparison between diffusion tensor imaging and anomalous diffusion metrics

OBJECTIVE: The goal of this work is to study the changes in white matter integrity in R6/2, a well-established animal model of Huntington’s disease (HD) that are captured by ex vivo diffusion imaging (DTI) using a high field MRI (17.6 T). MATERIALS AND METHODS: DTI and continuous time random walk (C...

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Bibliografiset tiedot
Julkaisussa:MAGMA
Päätekijät: Gatto, Rodolfo G., Ye, Allen Q., Colon-Perez, Luis, Mareci, Thomas H., Lysakowski, Anna, Price, Steven D., Brady, Scott T., Karaman, Muge, Morfini, Gerardo, Magin, Richard L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2019
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7837609/
https://ncbi.nlm.nih.gov/pubmed/30771034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10334-019-00742-6
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