Evaluation of the Immunogenicity of Mycobacterium bovis BCG Delivered by Aerosol to the Lungs of Macaques

Nine million cases of tuberculosis (TB) were reported in 2013, with a further 1.5 million deaths attributed to the disease. When delivered as an intradermal (i.d.) injection, the Mycobacterium bovis BCG vaccine provides limited protection, whereas aerosol delivery has been shown to enhance efficacy...

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Bibliographic Details
Published in:Clin Vaccine Immunol
Main Authors: White, A. D., Sarfas, C., West, K., Sibley, L. S., Wareham, A. S., Clark, S., Dennis, M. J., Williams, A., Marsh, P. D., Sharpe, S. A.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2015
Subjects:
Vaccines
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4550663/
https://ncbi.nlm.nih.gov/pubmed/26108288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00289-15
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