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Evaluation of the Immunogenicity of Mycobacterium bovis BCG Delivered by Aerosol to the Lungs of Macaques

Nine million cases of tuberculosis (TB) were reported in 2013, with a further 1.5 million deaths attributed to the disease. When delivered as an intradermal (i.d.) injection, the Mycobacterium bovis BCG vaccine provides limited protection, whereas aerosol delivery has been shown to enhance efficacy...

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Dettagli Bibliografici
Pubblicato in:Clin Vaccine Immunol
Autori principali: White, A. D., Sarfas, C., West, K., Sibley, L. S., Wareham, A. S., Clark, S., Dennis, M. J., Williams, A., Marsh, P. D., Sharpe, S. A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4550663/
https://ncbi.nlm.nih.gov/pubmed/26108288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00289-15
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