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Intranasal Administration of Mycobacterium bovis BCG Induces Superior Protection against Aerosol Infection with Mycobacterium tuberculosis in Mice

Despite the widespread use of Mycobacterium bovis BCG, the only licensed vaccine against tuberculosis (TB), TB remains a global epidemic. To assess whether more direct targeting of the lung mucosa by respiratory immunization would enhance the potency and longevity of BCG-induced anti-TB protective i...

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Bibliografski detalji
Izdano u:Clin Vaccine Immunol
Glavni autori: Derrick, Steven C., Kolibab, Kristopher, Yang, Amy, Morris, Sheldon L.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4266354/
https://ncbi.nlm.nih.gov/pubmed/25143340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00394-14
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